P2Y Purinoceptor Mediates Ca2+ Signaling in Duodenocytes and Involves Duodenal Mucosal Bicarbonate Secretion
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چکیده
منابع مشابه
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
Since little is known about the role of P2Y receptors (purinoceptors) in duodenal mucosal bicarbonate secretion (DMBS), we sought to investigate the expression and function of these receptors in duodenal epithelium. Expression of P2Y(2) receptors was detected by RT-PCR in mouse duodenal epithelium and SCBN cells, a duodenal epithelial cell line. UTP, a P2Y(2)-receptor agonist, but not ADP (10 m...
متن کاملP2Y receptors mediate Ca signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion
Dong X, Smoll EJ, Ko KH, Lee J, Chow JY, Kim HD, Insel PA, Dong H. P2Y receptors mediate Ca signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion. Am J Physiol Gastrointest Liver Physiol 296: G424–G432, 2009. First published December 12, 2008; doi:10.1152/ajpgi.90314.2008.—Since little is known about the role of P2Y receptors (purinoceptors) in duodenal mucosal bica...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.1202.5